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Best for: Conservative approach when uncertain about optimal timing, or when using whole-body cryotherapy chambers Exercise timing adds another layer of complexity

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Continued use of these models, including newer ones like gut organoids with human microbiota or brain-gut chip systems, will allow dissection of how specific microbes or metabolites act on specific brain cell types

Zoe Lees is a Medical Writer at MedExpress, specialising in clear, evidence-based health communications